PUBLICATIONS
Guy Heger, Mirta Dumančić , Ishai Luz , Maayan Vatarescu , Noam Weizman , Brian W Miller , Tomer Cooks , Lior Arazi. First measurements of radon-220 diffusion in mice tumors, towards treatment planning in diffusing alpha-emitters radiation therapy. 2024. Med Phys doi: 10.1002/mp.17020
Igea A, Martin OCB, Cooks T, Pateras IS. Editorial: Infectious disease agents and cancer. Front Cell Dev Biol. 2024, doi: 10.3389/fcell.2024.1388423
Joshua K Stone , Natalia von Muhlinen , Chenran Zhang , Ana I Robles , Amy L Flis , Eleazar Vega-Valle, Akihiko Miyanaga , Masaru Matsumoto, K Leigh Greathouse, Tomer Cooks, Giorgio Trinchieri, Curtis C Harris. Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development. Oncogenesis;13(1):13. doi: 10.1038/s41389-024-00513-6.
Or Michaeli, Ishai Luz , Maayan Vatarescu, Tal Manko, Noam Weizman, Yevgeniya Korotinsky, Alexandra Tsitrina, Alex Braiman, Lior Arazi, Tomer Cooks
Cell Death Dis. 2024 Jun 18;15(6):426.
NPJ Biofilms Microbiomes. 2023 Jun 3;9(1):30. doi: 10.1038/s41522-023-00400-9.
Nishri Y, Vatarescu M, Luz I, Epstein L, Dumančić M, Del Mare S, Shai A, Schmidt M, Deutsch L, Den RB, Kelson I, Keisari Y, Arazi L, Cooks T, Domankevich V. Diffusing alpha-emitters radiation therapy in combination with temozolomide or bevacizumab in human glioblastoma multiforme xenografts. Front Oncol. 2022 ;12:888100. doi: 10.3389/fonc.2022.888100
Welsh JA, Killingsworth B, Kepley J,... Cooks T, Harris CC, ... Jones JC. MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays. Cell Rep Methods. 2022 Jan 24;2(1):100136. doi: 10.1016/j.crmeth.2021.100136.
Prasad M, Zorea J, Jagadeeshan S, ...Cooks T, ...Elkabets M. MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer.. J Immunother Cancer. 2022 Mar;10(3):e003917. doi: 10.1136/jitc-2021-003917.
Igea A, Martin OCB, Cooks T, Pateras IS. Editorial: Reprogramming Stromal Cells in Chronic Inflammation and Cancer.
.Front Cell Dev Biol. 2021 Nov 5;9:728439. doi: 10.3389/fcell.2021.728439. eCollection 2021.
Shlomovitz I, Erlich Z, Arad G, Edry-Botzer L, Zargarian S, Cohen H, Manko T, Ofir-Birin Y, Cooks T, Regev-Rudzki N, Gerlic M. Proteomic analysis of necroptotic extracellular vesicles.
Cell Death Dis. 2021 Nov 8;12(11):1059. doi: 10.1038/s41419-021-04317-z.
Cooks T, Puzis R, Cohen O. Tissue resilience: lessons from social resilience. EMBO Rep 2021. e52926. doi: 10.15252/embr.202152926
Bhatta B, Luz, I, Krueger K, Teo FX, Lane DP, Sabapathy K, Cooks T. Cancer Cells Shuttle Extracellular Vesicles Containing Oncogenic Mutant p53 Proteins to the Tumor Microenvironment . Cancers 2021, 13(12), 2985;, https://doi.org/10.3390/cancers13122985
Bhatta B, Cooks T. Reshaping the tumor microenvironment: extracellular vesicles as messengers of cancer cells. Carcinogenesis. 2020 doi: 10.1093/carcin/bgaa107.
Azulay EE, Cooks T, Elkabets M.. Potential oncogenic roles of mutant-p53-derived exosomes in the tumor-host interaction of head and neck cancers.. Cancer Immunol Immunother. 2020 doi: 10.1007/s00262-019-02450-5.
Luz I, Cooks T Extracellular vesicles: what secrets do they hold inside?
Cell Death Dis. 2019; 10(6):406. doi: 10.1038/s41419-019-1643-9.
Pateras IS1, Cooks T Determination of Polarization of Resident Macrophages and Their Effect on the Tumor Microenvironment. Methods Mol Biol. 2019;1928:101-112. doi: 10.1007/978-1-4939-9027-6_7.
Myrianthopoulos V, Evangelou K, Vasileiou PVS, Cooks T, Vassilakopoulos TP, Pangalis GA, Kouloukoussa M, Kittas C, Georgakilas AG, Gorgoulis VG. Senescence and senotherapeutics: a new field in cancer therapy. Pharmacol Ther. 2019. pii: S0163-7258(18)30144-X. doi: 10.1016/j.pharmthera.2018.08.006
Bhatta B, Cooks T. Reshaping the tumor microenvironment: extracellular vesicles as messengers of cancer cells. Carcinogenesis. 2020 doi: 10.1093/carcin/bgaa107.
Cooks T, Pateras IS, Jenkins LM, Patel KM, Robles AI, Morris J, Forshew T, Appella E, Gorgoulis VG, Harris CC. Mutant p53 cancers reprogram tumor associated macrophages via exosomal miR-1246. Nature Comm. 2018;9(1):771. doi: 10.1038/s41467-018-03224-w.
Solomon H, Dinowitz N, Pateras IS, Cooks T, Shetzer Y, Molchadsky A, Charni M, Rabani S, Koifman G, Tarcic O, Porat Z, Kogan-Sakin I, Goldfinger N, Oren M, Harris CC, Gorgoulis VG, Rotter V. Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.
Tarcic O, Pateras IS, Cooks T, Shema E, Kanterman J, Ashkenazi H, Boocholez H, Hubert A, Rotkopf R, Baniyash M, Pikarsky E, Gorgoulis VG, Oren M. RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer. Cell Rep. 2016;14(6):1462-76
Reitkopf-Brodutch S1, Confino H, Schmidt M, Cooks T, Efrati M, Arazi L, Rath-Wolfson L, Marshak G, Kelson I, Keisari Y. Ablation of experimental colon cancer by intratumoral 224Radium-loaded wires is mediated by alpha particles released from atoms which spread in the tumor and can be augmented by chemotherapy. Int J Radiat Biol 2015; 91(2):179-86.
Cooks T, Oren M, Harris CC. Caught in the cross fire: p53 in inflammation. Carcinogenesis. 35:1680-90, 2014.
Cooks T, Harris CC. p53 mutations and inflammation-associated cancer are linked through TNF signaling. Mol Cell. 2014;56(5):611-2.
Cooks T, Pateras IS, Gorgoulis VG. When mutant p53 fires up. Cancer cell & Microen. 1: e135, 2014.
Cooks T, Pateras IS, Tarcic O, Solomon H, Schetter AJ, Wilder S, Lozano GC, Pikarsky E, Forshew T, Rosenfeld N, Harpaz N, Itzkowitz S, Harris CC, Rotter V, Gorgoulis VG, Oren M. Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer. Cancer Cell. 2013; 23(5):634-46.
2005-2012
Lazarov E, Arazi L, Cooks T, Schmidt M, Keisari Y, Kelson I. Comparative in vitro microdosimetric study of murine and human-derived cancer cells exposed to alpha particles. Rad Res. 2012; 177(3):280-7.
Horev-Droroi G, Cooks T, Bittan H, Lazarov E, Schmidt M, Arazi L, Efrati M, Kelson I, Keisari Y. Local control of experimental malignant pancreatic tumors by treatment with a combination of chemotherapy and intratumoral 224Radium-loaded wires releasing alpha-emitting atoms. Translat. Res. 2012; 159(1):32-41.
Cooks T, Tal M, Raab S, Efrati M, Reitkopf S, Lazarov E, Etzyoni R, Schmidt M, Arazi L, Kelson I, Keisari Y. Intratumoral 224Ra-Loaded Wires Spread Alpha-Emitters Inside Solid Human Tumors in Athymic Mice Achieving Tumor Control. Anticancer Res. 2012; 32(12):5315-21.
Arazi L, Cooks T, Schmidt M, Keisari Y, Kelson I. The treatment of solid tumors by alpha emitters released from (224)Ra-loaded sources-internal dosimetry analysis. Phys Med Biol. 2010; 55(4):1203-18.
Cooks T, Schmidt M, Bittan H, Lazarov E, Arazi L, Kelson I, Keisari Y. Local control of lung derived tumors by diffusing alpha-emitting atoms released from intratumoral wires loaded with Radium-224. Int J Radiat Oncol Biol Phys. 2009; 74(3):966-73.
Cooks T, Arazi L, Efrati M, Schmidt M, Marshak, G, Kelson I, Keisari Y. Treatment with interstitial wires releasing diffusing alpha-emitting atoms in combination with chemotherapy improved local tumor control and survival in squamous cell carcinoma bearing mice. Cancer 2009;115(8):1791-1801
Cooks T, Arazi L, Schmidt M, Marshak G, Kelson I, Keisari Y. Growth retardation and destruction of experimental Squamous cell carcinoma by interstitial radioactive wires releasing diffusing alpha-emitting atoms. Int J Cancer. 2008; 122(7):1657-64.
Arazi L, Cooks T, Schmidt M, Keisari Y, Kelson I. Treatment of solid tumours by interstitial release of recoiling short-lived alpha emitters. Phys. Med. Biol. 2007; 52 5025-5042.
Shalom-Feuerstein R, Cooks T, Raz A, Kloog Y. Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. Cancer Res. 2005; 65(16): 7292-300.
